The Seris or Comcaác are an indigenous people of the Mexican Sonoran desert.
Home of the Bufo Alvarius toad. The Seris currently live in two locations on the coast, Desemboque and Punta Chueca.

The Comcaác territory comprises an approximate area of 211,000 hectares, it is made up of a continental part and the largest island in Mexico, Isla Tiburón.